Feel Strong.
Live Strong.

A meticulously curated supplement formulation for high-achieving women seeking renewed vitality in perimenopause and beyond.

Why Femme-MD?

Because we know that with the right support, midlife can be a time of tremendous transformation.

Trustworthy

Trustworthy

100% of our products are practitioner-grade and curated by our founder Dr. Katie O'Brien MD, specialist in female hormone optimization.

Scientifically Backed

Scientifically Backed

We combine the most up-to-date insights from OB-Gyn, Endocrinology, and Sports Science to offer an elegant formulation that eliminates guesswork entirely.

Eco-Conscious

Eco-Conscious

LEED-certified manufacturing and CleanSeas members. We use significantly less plastic than competitors.

A Vision Born from Experience.

As physicians, athletes, and women navigating midlife ourselves, we understand the challenges of perimenopause and menopause firsthand. We experienced the gaps in care — brain fog, weight shifts, fatigue — and knew women deserved better.

We didn't want scattered solutions. We wanted clarity. So we created a physician-formulated protocol designed to support strength, energy, and metabolic balance at every stage.

Dr. Katie O'Brien, MD MPH IFMCP
Co-Founder & Medical Director

UMass Medical School • University of Arizona • Harvard School of Public Health

Institute for Functional Medicine Certified
Menopause Society Certified

100% Physician Curated
Medical Expertise
GMP Certified
Quality Standards
Clinically Formulated
Evidence Based

Lean Essentials Supports

  • Metabolic Heath & Glucose Control
  • Stress & Sleep Support
  • Healthy Detox Pathways
  • Cardiovascular & Bone Heath
  • GI Health & Microbiome Diversity
  • Body Composition & Lean Mass
  • Energy, Mood & Recovery
  • Inflammatory & Antioxidant Response
  • Thyroid, Adrenal & Female Hormone Balance
Women's Health MD Formulated

Twice daily formulation designed for the hormonal and metabolic transitions of midlife.

Third-party tested. Practitioner-grade ingredients. Third-party tested. No plastic bottles. No compromises. No guesswork.

MADE BY WOMEN IN IT. FOR WOMEN IN IT.

Energy & Mood

Energy & Mood

Methylated B vitamins and DHEA support healthy detox & adrenal health for sustained energy & mental clarity
Stress & Sleep

Stress & Sleep

Ashwagandha and Magnesium support healthy cortisol levels and muscle relaxation for restorative rest and recovery.
Weight Management & Microbiome Health

Weight Management & Microbiome Health

Berberine acts as a natural GLP-1 agonist, supporting healthy glucose regulation and body composition. Our probiotic also affects GLP-1 and promotes intake of less calories while promoting gut barrier function & microbiome diversity.
Anti-Inflammatory & Anti-Oxidant

Anti-Inflammatory & Anti-Oxidant

Vitamin D, High-Dose Omega 3, Magnesium and Berberine target inflammation at the cellular level. Spearmint & Green Tea Extract are potent anti-oxidants.
Sex Hormone Health

Sex Hormone Health

DHEA supports libido while multi-vitamin supports estrogen detoxification to dampen symptoms of perimenopause.
Thyroid & Bone

Thyroid & Bone

Selenium, Zinc, Calcium, Magnesium, Hydroxyapatite, Type 1 Collagen, Phosphorus and Vitamin D3+K are imperative for bone density and thyroid hormone conversion.

What's Inside Lean Essentials Premium?

Our comprehensive, physician-curated twice daily formulation designed to support sleep, metabolic health, hormone balance, energy, recovery and long-term vitality during perimenopause and menopause.

Ashwagandha
Bio-Active Berberine
Micronized DHEA
Max Lean Probiotic
Vitamin K2 + D3
Magnesium L-Threonate
Magnesium Chelate
Calcium, Type 1 Collagen
Phosphorus & Hydroxyapatite
High-Potency Multivitamin
Methylated B-vitamins
Omega-3 (High-Absorption EPA/DHA)
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Frequently Asked Questions

Everything you need to know about the Femme-MD.

  • FemmeMD is not merely a supplement company—it’s a clinical approach to women’s health.

    Every formulation we offer is carefully selected at the physician level, with a focus on purity, potency, and precision. Our products are designed to deliver targeted support for hormone health, metabolism, and body composition during perimenopause and menopause—without the guesswork or waste.

  • Yes. Every product is individually chosen based on quality, safety, and efficacy by our female MD founder. Our manufacturer is GMP certified, ensuring quality standards are not only met but dramatically exceeded.

  • Absolutely. Our products are free of all major allergens: gluten, soy, yeast, corn, tree nuts, dairy, peanuts, and sesame. All products contain non-GMO ingredients.

  • Lean Essentials Premium Pack delivers full-spectrum support for women in midlife. It is designed to optimize metabolism, support lean body composition, and promote hormone balance—while also addressing cardiovascular health, bone integrity, sleep, and stress.

    Think of it as your foundational, high-performance protocol for feeling strong, energized, and metabolically supported.

  • Yes, we understand life is busy. You can pause, skip, or cancel your monthly subscription at any time through your account portal.

  • We intentionally limit orders to a one-month supply to preserve the integrity of our formulations. Because our products contain highly active, carefully sourced ingredients, they have a shorter shelf life (approximately 60 days) compared to many mass-market supplements.

    This approach ensures you always receive fresh, potent products designed to deliver optimal results.

  • Lean Essentials Premium Formulation (Top Tier):

    Our most advanced, MD-curated formulation is designed specifically for women in perimenopause and menopause—supporting weight management, lean body composition, glycemic balance, cardiovascular and bone health, hormone support, recovery, sleep, and stress resilience. This comprehensive, high-potency blend delivers synergistic ingredients at clinically meaningful doses to support whole-body optimization during this transition. For women seeking the most complete and effective daily foundation, this is our gold standard.

    Lean Essentials Foundations (Entry-Level / Foundational Formula):

    This MD-curated foundational formula offers targeted support for women in perimenopause and menopause, with a focus on weight management, metabolic health, energy, mood, and overall wellness. Designed as a simplified, lower-cost option, it provides meaningful daily support for those just getting started or not ready to commit to a more comprehensive regimen. A smart, approachable first step toward feeling your best—with room to build over time.

  • The health of our planet is incredibly important to us, and we’ve intentionally designed our packaging to reduce unnecessary waste. Our products are packaged in recyclable cardboard rather than traditional plastic bottles, significantly lowering overall plastic use and environmental impact. While we do use small sachets to preserve product quality and freshness, this approach still results in far less plastic compared to standard supplement packaging—offering a more thoughtful balance between sustainability, safety, and efficacy.

  • The short answer is NO. While many of the individual ingredients in our formulation meet high-quality standards and are NSF certified on their own, the inclusion of DHEA means the finished product cannot carry NSF Certified for Sport designation.

    DHEA (dehydroepiandrosterone) is not permitted under NSF International / Certified for Sport because it acts as a hormone precursor, converting in the body to testosterone and estrogen, which can influence performance. As a result, World Anti-Doping Agency (WADA) classifies it as a prohibited anabolic agent.

    Importantly, this restriction is specific to competitive sport standards—not general clinical use. In fact, this is exactly why we include DHEA in our formulation: to thoughtfully and naturally support healthy testosterone levels in women, which can play a key role in body composition, energy, libido, and overall vitality during perimenopause and menopause.

  • YES! Our formulations are built on a foundation of rigorous safety, quality, and clinical integrity. Every product undergoes comprehensive testing to verify label accuracy and screen for impurities and allergens, supported by advanced, on-site quality control laboratories using best-in-class chemical and biological analysis. We also partner with leading independent labs for additional validation, ensuring every batch meets the highest standards and is backed by a detailed certificate of analysis. Manufactured in an ultramodern, U.S. Food and Drug Administration cGMP-certified facility, our products adhere to strict guidelines for design, monitoring, and quality control. From cutting-edge manufacturing and packaging systems to environmentally controlled storage and integrated research facilities, every step is designed to ensure consistency, purity, and efficacy—so you can feel confident in what you’re putting into your body.

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